7 May 2010

The e-cigarette – personal nicotine vapouriser

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3 June 2009   Health warning:

Precautions required with e-cigarettes

Avoid bottled nicotine. Liquid nicotine (e-liquid) is commonly sold in small bottles of up to 30 mL or more, on the internet, or from stores in the USA, often meant to last consumers one month; and often unlabelled as to nicotine dose. Health New Zealand Ltd does not recommend sale or use of e-liquid permitting a lethal dose of nicotine to be accidentally swallowed. Nicotine solution sold in child-proofed cartridges or unopenable disposable e-cigarettes or atomisers avoids this risk.

Acute poisoning risk. For a child, the lethal dose is 10 mg nicotine. Many bottles on sale contain many times this amount. Even if the cap of a liquid nicotine bottle is child proofed, the risk remains if someone else leaves it open. For adults, absorption of a fatal dose of 40-60 mg of nicotine could rapidly occur due to spilling the liquid on one’s skin while using liquid nicotine to (cheaply) fill an e-cigarette – a risk heightened by inattention (distraction, fatigue, alcohol, drugs). (Wash it off immediately). Gloves should always be worn.

Avoid gravity feed. E-cigarettes should not be tipped up above mouth level, as the e-cigarette liquid can ooze out and drain nicotine on to the lips.

Avoid child-openable brands of e-cigarette and refill cartridges. Some brands can be pulled apart or opened by young children, giving access to the nicotine solution soaking the wick. Flavours in the liquid can mask the bitter nicotine taste.

 Safety results, April 2009:

E-cigarette Safety: Ruyan e-cigarette benchtop tests. Poster 5-11. See. www.healthnz.co.nz/DublinEcigBenchtopHandout.pdf  The poster itself is found in the following two powerpoint files: http://www.healthnz.co.nz/DublinEcigPoster1.ppt and http://www.healthnz.co.nz/DublinEcigPoster2.ppt 

The mist of the e-cigarette has been rigorously tested in the laboratory. Of over 60 priority-listed cigarette smoke toxicants tested, trace levels for some only were detected in the mist of the Ruyan® e-cigarette. The results are to be submitted for publication shortly in a peer-reviewed journal.  On the basis of findings to date, inhaling mist from the e-cigarette is rated some two orders of magnitude (100 times) less dangerous than smoking tobacco cigarettes. The nicotine dose per puff is comparable to that of a medicinal nicotine inhaler. E-cigarette nicotine is apparently not absorbed from the lung, but from the upper airways.

 

Efficacy results, April 2010

 

On behalf of Ruyan, manufacturer of the Ruyan V8 e-cigarette, Health New Zealand Ltd sponsored this research carried out in Auckland by researchers at the School of Population Health, University of Auckland. See http://www.healthnz.co.nz/2010%20Bullen%20ECig.pdf  The study was published in Tobacco Control in April 2010.

 

Update on the e-cigarette, October 2009

http://www.healthnz.co.nz/ElectronicCigsDarwinOct09.pdf

TV3  2008  The Ruyan V8 Classic. An LED lights up the end. The white part is the battery. The nicotine is housed just upstream of the fingers.

 

Legal status (New Zealand)

An e-cigarette can be imported for sale once the device is registered, but not with nicotine in the cartridges.

Nicotine comes under Medicines Act and approval for a new nicotine medicine is very expensive and takes several years. Import of e-cigarettes and nicotine cartridges for personal use is allowed.

 

About the device

This nicotine inhaler mimics the smoking experience more closely than any smokeless product to date and provides nicotine without causing smokers to cough.

It looks and acts like a cigarette.

It gives the pleasure of drawback, and a nicotine effect within 15 minutes. It is likely to be popular as a much cleaner and safer alternative to smoking, by eliminating the tar and the toxicant gases. More frequent puffs will deliver more nicotine, which is otherwise much less than from a tobacco cigarette. Holding the puff in the mouth for longer may help.

 

Extended use and misuse of e-cigarette

The e-cigarette is an inhaler but does not deliver nicotine deeply into the lung. Its ability with other drugs is untried. Nicotine by e-cigarette is absorbed from the throat and upper airways and not from the lung.

Cannabis

People mixed tobacco with marijuana for smoking long before e-cigarettes, and smoking is the most dangerous way to consume cannabis or tobacco.

Devices for heating and vaporizing cannabis long preceded the e-cigarette. Whether or not e-cigarettes could be used for that purpose, no smoke will be inhaled.  

It is not known whether the e-cigarette would facilitate absorption of THC, the active ingredient in cannabis. The e-cigarette vapourises liquid but does not burn plant material such as marijuana or tobacco. If cannabis is vaped by e-cigarette, rather than combusted and smoked in a joint,  then no smoke is inhaled. Lung cancer  occurs after many years of smoke inhalation, of either tobacco or marijuana smoke.

E-cigarette vaping  is likely to be  a less harmful way to obtain cannabis than smoking it, but we have no test results to confirm that.

For example, the illegality of cannabis makes adulteration possible, and prevents legal controls on its production. Also research safeguards are lacking. The effect of inhaling and vaporizing THC in the e-cigarette liquid has not been tested and researched by anyone to our knowledge.

 

Note: Health New Zealand Ltd has no financial interests in any nicotine, tobacco or pharmaceutical company.

The e-cigarette provides a safer alternative for smokers. No deaths have yet been reported from e-cigarette use.

Dr Murray Laugesen chair; Prof Ross McCormick, Sir John Scott KBE, Trish Fraser MPH, Dr Marewa Glover, Trustees 

Making it easier to quit smoking for good © 2010 End Smoking NZ