28 September 2009

Sugars in cigarettes increase cancer-causing formaldehyde gas in smoke  - some sugars  added during manufacture

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The case for regulations in the next Smoke-free Environments Amendment Bill, to stop this practice.

Regulatory powers are already in the SFE Act, at section 31. Regulations for cabinet approval are needed.

 

Summary

Sugars, in tobacco or added at the factory, when burnt, generates in mainstream smoke the gas formaldehyde, a well-known carcinogen.

This argues for regulations to stop adding sugar to smoking tobacco products to sweeten cigarettes for young people. Such regulations could further lower adolescent smoking rates.  

Selecting tobacco blends for their sugar content is common practice in cigarette manufacture. But adding sugar is something else – adding to young peoples’ cancer risks, just to sell more product. We do not know how much sugars are added to NZ tobacco, but no law prevents it.

Argument

·         Sugars in cigarettes sweeten the bitter taste of nicotine in tobacco to make it easier to learn to smoke and keep on smoking cigarettes.  

·         Sugars are the main additive to tobacco in NZ by weight.[1]

·         Tobacco industry scientists[5] shows sugars burnt in cigarettes generate formaldehyde, a cancer- causing gas in cigarette smoke. 

·         Formaldehyde is a carcinogen and in the top 9 toxicants for which WHO Tob Reg Committee has recommended reduction.[2]

·         Of 32 smokers, 29 had formaldehyde-DNA adducts (in their white blood cells, against 7 out of 30 nonsmokers. (p<0.001) [3]

 

 

 

[1]Manufacturers returns at www.ndp.govt.nz show that BATNZ had undertaken not to add any more than 5.65% of sugars, syrups, honey etc. to its cigarettes for 2008. No regulations restrict what they add or how much.

[2] Burns DM, Dybing E, Gray N, Hecht S, Anderson C, Sanner T, O’Connor R, Djordjevic M, Dresler C, Hainaut P, Jarvis M, Opperhuizen A, Straif K. Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg Proposal. Tobacco Control 2008; 17:132-41.

[3] Mingyao Wang, Guang Cheng, Silvia Balbo, Steven G. Carmella, Peter W. Villalta and Stephen S. Hecht

Clear Differences in Levels of a Formaldehyde-DNA Adduct in Leukocytes of Smokers and Nonsmokers. Cancer Research 69, 7170, September 15, 2009. Published Online First September 8, 2009.

 

[4] Reinskje Talhout, Antoon Opperhuizen, Jan G.C. van Amsterdam http://www.ncbi.nlm.nih.gov/sites/entrez PMID: 16904804.

 

[5] Baker RR. Steven Coburn and Chuan Liu

Food Chem Toxicol. 2006 Nov;44(11):1799-822. Epub 2006 Jun 7    PMID: 16859820

[6] http://tobacco.health.usyd.edu.au/ site/gateway/docs/pdf2/pdf/PM2000764233_4239.PDF

 

 

 

Sugars as tobacco ingredient: Effects on mainstream smoke composition [4]




References and further reading may be available for this article. To view references and further reading you must purchase this article.

 

Sugars are found in the Virginia tobacco used in NZ cigarettes, and are also frequently added during the manufacturing process. This review describes the fate of sugars during tobacco smoking, in particular the effect of tobacco sugars on mainstream smoke composition. In natural tobacco, sugars can be present in levels up to 20 wt%. In addition, various sugars are added in tobacco manufacturing in amounts up to 4 wt% per sugar. The added sugars are usually reported to serve as flavour/casing and humectant. However, sugars also promote tobacco smoking, because they generate acids that neutralize the harsh taste and throat impact of tobacco smoke. Moreover, the sweet taste and the agreeable smell of caramelized sugar flavors are appreciated in particular by starting adolescent smokers.

Finally, sugars generate acetaldehyde, which has addictive properties and acts synergistically with nicotine in rodents. Apart from these consumption-enhancing pyrolysis products, many toxic (including carcinogenic) smoke compounds are generated from sugars. In particular, sugars increase the level of formaldehyde, acetaldehyde, acetone, acrolein, and 2-furfural in tobacco smoke. It is concluded that sugars in tobacco significantly contribute to the adverse health effects of tobacco smoking.

 

 

 

 

The generation of formaldehyde in cigarettes--Overview and recent experiments [5]

 

We are indebted to research scientists at BAT

Research and Development Centre, UK, for the following information:

 

“..all tested sugars added to tobacco increase the yield of formaldehyde in mainstream cigarette smoke under ISO standard smoking machine conditions. Increases up to 60% are observed at maximum sugar levels used on cigarettes.”

The (natural) reducing sugar content of NZ cigarettes using Virginia tobacco eg Rothmans, is around 13 to 15%, according to a 1973 BAT document. [6]

Sugar consumption in recent years has increased enormously – it is used in fast food and fizzy drinks, in alcopops, and now added to cigarettes. Only in cigarettes does sugar generate formaldehyde.

 

Bottom line: Will this policy reduce numbers smoking, and numbers of cigarettes sold? We think so.

 Dr Murray Laugesen QSO chair; Prof Ross McCormick, Sir John Scott KBE, Trish Fraser MPH, Dr Marewa Glover, Trustees

Making it easier to quit smoking for good © 2009 End Smoking NZ